Moode USB Output

[pyhfsg]

I have a Raspberry Pi 4 and a pair of Klipsch R-51PM Active Speakers (running Moode 6.7.1). Since the speakers have a built-in DAC and a 100% digital amp, I want to keep the signal digital throughout the entire pipeline -- so I figured I'd use the USB output on the Pi. Moode recognizes the speakers, but no audio will come out of them. One time (in ~10 boot-ups) they did actually work with the settings below:

I2S = None
MPD = Set to my speakers (Moode sees them no problem)
Volume Control = Hardware
Volume Control = Disabled / 0db
DSD over PM = No
UAC2 Fix = No
Tried USB 2.0 and 3.0 ports (the one time it worked was on USB 3.0)

Moode seems to think it's playing to the speakers; there are no errors or warnings. I tried hooking up another powered USB speaker (SoundBlaster Roar 2 with built-in DAC and Amp) and it works perfectly (using the settings above). The Klipsch work fine with my windows 10 computer. I'm stumped.

I have HDMI turned off and am accessing Moode through the Pi 7" touchscreen (which by the way is absolutely amazing with the Moode Theme "PUre Black" which works perfectly on a screen that size).

Also, would there be any audio quality improvement if I purchased a HAT with Toslink Audio as opposed to the native R Pi 4 USB audio?

Any advice for a newbie?

Newbie here. I am in the exact predicament. I got my RPi4B 2 days ago and wanted to connect my PSB Alpha AM3 active speaker to the RPi USB port.I tried Volumio for the last 2 days, could not get it work, there were so many issues with the installation, i gave up. Now, I am trying Moode and must said the installation was smoother, Moode has no problem of recognising the active speaker connected to the USB port. But there is no sound coming out even though I see it is playing. I tried your settings above but no difference. Wonder if you managed to resolve the problem.