I've been doing extensive troubleshooting random dropouts during playback of DSD64 files on my setup consisting of an RPi 3 B+ with a USB DAC (Benchmark DAC3 HGC). This DAC requires DoP mode to be enabled in the MPD config.
The two things I've found to have the most impact on performance were switching to the 32 bit 'legacy' version of mOode and setting the CPU governor to 'performance' instead of 'ondemand'.
Lastly, I also had some strange messages in my logs related to CIFS (my music folder is being shared from a Mac mini). It was writing 'CIFS: __readahead_batch() returned' repeatedly to /var/log/messages as I was streaming a file. That also seemed to be causing dropouts. I disabled and re-enabled sharing on the Mac and the error went away.
Hope this helps!
The two things I've found to have the most impact on performance were switching to the 32 bit 'legacy' version of mOode and setting the CPU governor to 'performance' instead of 'ondemand'.
Lastly, I also had some strange messages in my logs related to CIFS (my music folder is being shared from a Mac mini). It was writing 'CIFS: __readahead_batch() returned' repeatedly to /var/log/messages as I was streaming a file. That also seemed to be causing dropouts. I disabled and re-enabled sharing on the Mac and the error went away.
Hope this helps!