Allo USBridge Signature

[vmirmow]

I could use some help...

Sadly yesterday evening clicks and pops suddenly occurred during a listening session. I tried changing the MPD settings Audio buffer from 4096 with incremental steps to 20480 and also the fill before play from none to 30% but notting seems to work. I also did a few reboots and checked my cables. 
With some songs I get clicks within a minute, with others it takes longer. 
The weird thing is that the day before I did not hear clicks and pops with 30% fill before play and 4096 buffer. 

Any tips on what to do next?

PS,
I only play aiff or mp3 files and don't do resampling.

I was getting occasional clicks/pops too and found that they went away after changing the CPU governor from On-Demand to Performance. Still using default audio buffer settings.